Neuroengineering IGERT Students Experience Interdisciplinary Research

Neuroengineering IGERT graduate student Olivia Cangellaris
Neuroengineering IGERT graduate student Olivia Cangellaris

One student wants to discover how the brain enables complex thought, such as philosophy. Another wants a field rewarding enough to get him out of bed and to work every morning. Another student, who heard about the IGERT program while jogging, finds the psychology-engineering intersection intriguing and the engineering tools crucial to his work. Still another saw the IGERT as an opportunity to acquire resources, knowledge, and connections in the field of engineering that she wouldn't have had otherwise. No matter why students chose the Neuroengineering IGERT at Illinois, they find interdisciplinary research at the intersection of neuroscience and engineering to be challenging, yet exciting.

Funded by a National Science Foundation Integrative Graduate Education and Research Traineeship (IGERT) grant, the five-year Ph.D. program, "Neuroengineering: A Unified Educational Program for Systems Engineering in Neuroscience," is starting its fourth year and currently has 45 graduate students enrolled. Coming from a range of disciplines (i.e., neuroscience, psychology, molecular and cellular biology, electrical and computer engineering, bioengineering, and the medical scholars program) the students are interested in neuroengineering for reasons that are just as diverse.

For example, Olivia Cangellaris, whose undergraduate degree is in bioengineering, is pursuing both a Ph.D. in Bioengineering and an M.D. in the Medical Scholars Program. Cangellaris has been interested in the brain, particularly "what it is that makes our brains work," ever since middle school. She recalls that reading Jostein Gaardner's The Solitare Mystery, with its subtle philosophical theme, piqued her interest in philosophy. How did she get from Plato and Socrates to brain surgery? "I was just interested in the brain and the fact that a philosopher is able to ask the kinds of questions they ask and question things that are not physically apparent—ask these very abstract questions. I guess I've just always been fascinated with how complex our brains are and how that enables us to be who we are, and do what we do, and think what we think."

Erik Johnson
Erik Johnson, IGERT fellow from Electrical Engineering, acts as a guinea pig to have his brain waves analyzed.

It was the IGERT's interface of neuroscience and engineering that intrigued Erik Johnson, an Electrical and Computer Engineering Ph.D. student. In his fourth year in the IGERT, Johnson is specializing in bioimaging: imaging technologies and techniques for neuroscientists.

"As an engineer, I'm very interested in signal processing, data analysis, and the mathematics behind it. But without a driving application, I didn't really see the purpose of doing the mathematics for mathematics' sake. That's not the kind of thing that would get me out of bed in the morning and get me excited about going to work. There are just so many potential applications in this emerging field of neuroengineering, and exciting that you also get to define some of them yourself. So that, to me, has been a big draw and was actually the reason that I joined the IGERT specifically—to be able to pursue those sorts of applications. I think this is a really exciting place where engineers can be motivated by new problems and forced to find solutions that actually have practical value to neuroscientists."

Almost as diverse as their reasons for studying neuroengineering are some of their career goals. For example, Cangellaris wants to practice brain surgery. However, because she's also interested in how technology is influencing medicine, she wants to use technology to treat or manage diseases. "I do think that the way that the medical field is evolving, the way biotechnology is advancing, all of that is shaping how medicine is being performed." She would ultimately like to meld a clinical approach with a technical background, eventually working at a hospital partnered with a research institution in a climate that fosters "dialogue between clinicians and researchers in terms of how you go about approaching the problem and how you go about trying to fix it."

Johnson's career goals? Do neuroengineering research in a national lab or teach neuroengineering in academia.

So far, while the students are finding the interdisciplinary collaboration and communication with people in disciplines other than their own to be challenging, they also find it to be fulfilling in that it causes them to grow as researchers.

Olivia Cangellaris
Olivia Cangellaris at work in Martha Gillette's lab in Morrill Hall.

According to Cangellaris, her favorite part of the program is rubbing shoulders with people from different disciplines. "It's really great to have that natural integration of different fields because it forces you to think differently. I think that's what makes a better researcher; it's somebody who can ask questions that they're not comfortable with and take that all into consideration as they're designing their experimental platform, then that continuous dialogue helps shape you into a better researcher.

Has she learned a lot so far from the interdisciplinary collaboration? "It's filled in some holes, but in the lab meetings, the questions that people ask me after I present, I think it's more so informed me of what I don't know. Because people ask me questions, and I say, 'Oh, I didn't think about that.' Because I'm not at that point where I move between thinking like a neuroscientist and an engineer; I think I'm still approaching things from an engineering standpoint. The questions that I'm asking do not include questions that are obvious to a cell biologist. So working in this lab has been great because it's really helping me figure out and identify what I know and what I don't know—what I still have to learn."

Part of the brain-machine interfacing track, Cangellaris is looking forward to the interdisciplinary project this spring. "It's this establishment of a dialogue and learning how to talk to somebody who doesn't necessarily have the same background as you and to convey ideas and to ultimately come up with something new."


Clockwise: Neuroengineering IGERT students Jamie Norton and Erik Johnson look at data from a brain cap that measures a person's brain activity.

Engineer Erik Johnson admits that communicating with people in other disciplines can sometimes be a challenge.

"Engineers, we are fairly well known for our ability to talk in jargon, especially mathematics. So often when we're talking a potential project up to someone, we have to be very careful about the words we choose, motivate everything well with intuitive examples. On the other hand, the neuroscientists are very well known for all the jargon that they use. I still struggle to keep up with them when they start rattling off brain structures. I know some of them…I'm way ahead of, say, the other students in my lab who have not taken any neuroscience courses and have not been through the IGERT program. It's certainly helped a lot with the communication issue. It doesn't just go away magically. It's something that we're aware of and work at."

Johnson's take on the program? "I think it's really fun. It's really exciting. It's cool to actually be able to tell my friends that I'm a neuroengineer. There are really only a handful of programs in the country trying to do this kind of work…The field as a whole is exciting and emerging. The field is maturing as a whole, so it's really exciting to see. I think a lot of really cool stuff is going to come out of it."

Neuroengineering IGERT fellow Jamie Norton, who is working in brain-machine interfaces
Neuroengineering IGERT fellow Jamie Norton, whose research is brain-machine interfaces

Two other grad students, Jamie Norton and Danielle Dickson, entered the Neuroengineering IGERT from the psychology side.

Norton, who is in his third year in the Ph.D. program, ended up at Illinois through a very circuitous route. While working in Boston after getting his Bachelor's in psychology in Florida, he was running over the noon hour with a jogging buddy/mentor who, having read about NSF's IGERT program, encouraged him to apply. He did some research, found the IGERT at Illinois to be the most interesting and the best fit, and applied.

Danielle Dickson, who majored in cognitive science and linguistics as an undergrad, is in the Psychology Department's cognitive neuroscience division. While she chose the imaging track, she is also interested in brain-machine interfaces because they utilize her primary research method of EEG (Electroencephalography) to record electrical activity of the brain. In one project, she also uses fMRI (Functional Magnetic Resonance Imaging), which measures brain activity via images of blood oxygenation levels in the brain.

Has the Neuroengineering IGERT given these students from non-engineering backgrounds a handle on engineering?

Dickson reports increased understanding of engineering jargon: "I feel a lot more empowered to actually read the methods sections of these papers and be more critical, 'Why did they choose to do it this way? This is unusual,' whereas before, I would have just been like, 'Yea, yea, whatever. They used a 90-degree flip angle and a this-by-this voxel whatever, whatever.'"

While Norton's understanding of engineering has increased, the networking and relationships the program has fostered with engineers are key to his work: "It also empowers you to know who to talk to when there are problems. So it's not just your own knowledge, but knowing where you should look for expert knowledge. In my case, it's really enabled me to talk more with the signal processing guys, really understand the theories that they're applying to their research. Then we're able to collaborate better, and I can tell them what I'm actually trying to accomplish, and then they can think about what methods within their toolbox really apply. You really are empowered just to say, 'I have this specific question I'm trying to answer; I know that this person exists in this other lab, that I've never worked with, but works in this area,' and you can just go talk to them and have a conversation."

Danielle Dickson, an IGERT fellow from Psychology's Cognitive Neuroscience division.
Danielle Dickson, a Neuroengineering IGERT fellow from Psychology's Cognitive Neuroscience division.

Having been exposed to engineering courses through the program, do they now consider themselves to be neuroengineers? "I think it's a side project kind of work for me," answers Dickson, "where I have power to use other techniques and ask questions that I never would have been able to ask before or know how to ask. Until you're exposed to all of these individuals here in the program, you don't even really know, necessarily, that there are people out there whose whole life it is just doing x, y, and z. There are such different problems that they are solving that you wouldn't even know to ask. Now I can better communicate with others and use their input in ways that I wouldn't have thought to use."

But she does consider the engineering knowledge to be beneficial to her work. In a scenario where she is buying new equipment for a lab, she envisions drawing upon her newly-gained knowledge. "You want to know, 'What settings should I use? What kind of materials? Why would you use this amplifier instead of this amplifier? And when you actually open the book, previously it would have been a bunch of jibberish, and now I actually understand, 'Oh, that's why you would want to buy this amplifier instead of this amplifier.' So I can see that it's never going to totally disappear from your life, because it's really valuable information, but it's not necessarily going to guide my work in the way that it guides some other students."

On the other hand, Norton believes engineering is crucial to his work in brain-computer interfaces. "You can't build a brain-computer interface without psychology, neuroscience, and engineering. It's just not possible. You can look at one side, and a lot of researchers do. But I don't think you're going to get anywhere in the long run if you don't consider all angles of the problem. That includes, what are the underlying brain processes? Hardware engineers: we work a lot with the material sciences group on campus…One of my favorite collaborators in my lab is a circuits guy named Dennis. He may be able to improve the equipment that I'm using. So without understanding what they're doing, you don't understand how it fits into the system."

Jamie Norton and Erik Johnson
Left to right: Jamie Norton and Erik Johnson measure brain waves in a Beckman lab.

Norton goes on to describe a recent successful collaboration in signal processing. While classifying bad signals, he needed a method which allowed him to get as much information out of the signal as possible. He approached Erik Johnson, who responded, "Yea, we could do this." They've already implemented it, and it improves the signal quality. "So, yea," acknowledges Norton, "if I want to stay in brain-computer interfaces, it's absolutely crucial that I stay in neuroengineering."

Norton considers himself a neuroengineer. According to Dickson, "He's the most neuroengineering person that you're probably going to [find]. Everyone else kind of moves more toward, 'Well, I like the brain, but I'm going to be an engineer, and the brain is cool,' and then I'm more of a, 'Well, the engineering tools are critical to get my research done, but I'm not myself super motivated to tweak the existing tools that have worked for 30 years,' but Jamie is. He has to."

Regarding the somewhat nebulous definition of what a neuroengineer is, the students have evidently devised a kind of continuum. "We talk about it being on a spectrum. It's not a 0 or a 1; it's between 0 and 1. If you say "1" was engineering…" Then they went on to assign various members of their cohort. Most were assigned "slightly in the middle." Says Dickson, "There are people who aren't on the spectrum at all. I think cognitive psychologists aren't really on the spectrum at all." Despite her not considering herself to be a neuroengineer, she does consider herself to be on the spectrum. ("It's like a disorder," quips Norton, in an aside.) Dickson ranks Norton as very central; she considers herself to be closer to the Neuroscience side. "It's a good way of thinking about it that accurately captures the diversity of the group,"she concludes.

Danielle Dickson and Doug Johnson
Danielle Dickson and Doug Johnson discuss her research during a chance encounter at Beckman Institute.

If they had to go back, would they choose to do the Neuroengineering IGERT again? "I can't imagine not having that foundation on which to go forward," admits Dickson. "There's so much information that I learned that I didn't know that I needed or could have used, but having it now is invaluable…I can imagine not having it, and that outcome isn't as good as this outcome. I would still be recording brain activity, and I would never know that this world existed!"

Norton agrees. "I did all psych through undergrad, and without the engineering background, especially the signal processing that we learned with Doug, a lot of the stuff just isn't possible. I can't imagine not having the background. Instead of being a curiosity, it now guides my research, as opposed to before, it was an area you avoid because you don't understand."

For more on this topic: IGERT Trains Students at the Intersection of Neuroscience and Engineering looks this cutting-edge program and its goals.

Story and photographs by Elizabeth Innes, Communications Specialist, I-STEM Education Initiative
More: Biology, Engineering, Funded, Graduate Education Reform, IGERT

Jamie Norton and Erik Johnson
Left to right: Jamie Norton and Erik Johnson demonstrate how electromyography, the electrical activity generated by muscle contraction, can be harnessed, for example, to fly a helecopter.




Program prepares STEM educators to teach all students

November 30, 2021
This summer, a group of educators gathered to learn about engaging STEM activities they can do with their students.
Full Story

Research Experiences for Undergraduates (REU) program

November 11, 2021
Undergrads get a taste of research through I-MRSEC’s REU program.
Full Story

Goldstein’s Renaissance Engineering Summer Camp

November 1, 2021
Goldstein’s Renaissance Engineering Summer Camp Incorporates Art, Design, Mechatronics, and Mentoring
Full Story

TechTogether Chicago to Redefine the Hacker Stereotype

July 10, 2021
New workshops that can help inspire students to pursue careers in technology..
Full Story

Aerospace Engineering Launches Virtual Summer Camps to Pique Students’ Interest in Aero.

July 2, 2021
Design an aircraft then watch it soar after launching it with a huge rubber band. Build a Mars lander to safely transport a real egg, then test the contraption by dropping it from a second story window.
Full Story

Undergrads Experience Materials Science Research Courtesy of the I-MRSEC REU

June 16, 2021
Ten undergraduate students are spending the summer of 2021 discovering what research is like.
Full Story

MatSE Afterschool Academy

MatSE Afterschool Academy

June 14, 2021
MatSE Afterschool Academy to Introduce Students to Materials Science and Beyond.
Full Story

Taylor Tucker Embraces Multidisciplinary Interest

Taylor Tucker Embraces Multidisciplinary Interest

June 14, 2021
Taylor Tucker Embraces Multidisciplinary Interest While Researching Task Collaboration.
Full Story

Exposes Franklin Middle Schoolers to Science, CS

What Studying Engineering at Illinois is Like?

May 25, 2021
NSBE’s Michaela Horn Exposes Franklin Middle Schoolers to Science, CS, and What Studying Engineering at Illinois is Like.
Full Story

Jenny Saves a Convertible.

Children’s-Book-Writing Duo/

May 19, 2021
Convertibles and Thunderstorms—Children’s-Book-Writing Duo on Their Way Thanks to Illinois Training and Encouragement from Mentors.
Full Story

Improve Learning in Engineering

Improve Learning in Engineering

May 17, 2021
Liebenberg Espouses Mini-Projects to Engage Students Emotionally, Improve Learning in Engineering.
Full Story

Joshua Whitely makes an adjustment to the 3D Bioprinter during the demo.

BIOE435 Capstone Projects

May 12, 2021
BIOE435 Capstone Projects - BIOE Seniors Use Knowledge/Skills to Problem Solve.
Full Story

Elani and Gonzalo shine a UV light on a rose that has absorbed a solution that has made it fluorescent.

Illinois Scientists Shine a (UV) Light on Fluorescence

May 7, 2021
What is fluorescence? What causes it?
Full Story

Joshua Whitely makes an adjustment to the 3D Bioprinter during the demo.

HackIllinois 2021 “Rekindled Connections” With The Tech Community

May 5, 2021
Annual student hackathon HackIllinois with the aim of developing projects on current problems facing society.
Full Story

A Shane Mayer-Gawlik image of the Bridger Aurora, part of his Night Skies photography collection exhibited at the Art-Science Festival.

The Art-Science Festival

April 26, 2021
Illinois Art-Science Festival: Illuminating the Universe...from the Quantum World to the Cosmos.
Full Story

Joshua Whitely makes an adjustment to the 3D Bioprinter during the demo.

Illinois Engineering Seniors Prepared to Change the World

April 22, 2021
Ready. Set. Go! Illinois Engineering Seniors Prepared to Change the World.
Full Story

HML 2021 Virtual Health

HML 2021 Virtual Health

April 19, 2021
Make-a-Thon Gives Citizen Scientists a Shot at Making Their Health-Related Innovations a Reality.
Full Story

I-MRSEC’s Music Video

I-MRSEC’s Music Video

April 7, 2021
I-MRSEC’s Music Video for EOH ’21 Plugs Graphene, 2D Materials
Full Story

Health Make-a-Thon Orientation

HML 2021 Health Orientation

March 30, 2021
HML 2021 Health Make-a-Thon Orientation Prepares Finalists for Competition.
Full Story

Andrea Perry shows Franklin students how to take apart the magnetic drawing board they received in their kit

Musical Magnetism

March 25, 2021
Musical Magnetism: Encouraging Franklin Middle Schoolers to Express Science Via the Arts.
Full Story

Carmen Paquette street performing.

Love of Science

March 9, 2021
Paquette Conveys Her Love of Science, Dance to Franklin STEAM Students Via Musical Magnetism.
Full Stroy

An Engineering Exploration participant exhibits the tower they built as part of the engineering challenge related to Civil Engineering

Engineering Exploration

March 2, 2021
SWE’s Engineering Exploration Outreach Lives Up to Its Name.

ChiS&E’s Family STEM Day

ChiS&E’s Family STEM Day

February 23, 2021
Helps Chicago Youngsters Progress Along the STEM Pipeline Toward Engineering.

Kathny Walsh

Kathy Walsh

February 17, 2021
On Her First Foray into STEAM, Kathy Walsh Acquaints Franklin Students with Microscopy, Haiku.

ChiS&E student

ChiS&E CPS Students

January 19, 2021
Illinois Undergrads Encourage ChiS&E CPS Students Toward Possible Careers in Engineering.

I-MRSEC’s Music Video

CISTEME365 Provides Year-Round PD/Community

January 4, 2021
to Illinois Teachers in Support of Informal STEM Education Efforts to Underserved Students.